Perinatal risk factors of infants in case control comparison of 17 T or Tk antigen activated infants and 28 weight and gestation matched controls who developed NEC after September 1991
| Variable | T/Tk antigen activated infants (%) | Matched control infants (%) | p Value |
|---|---|---|---|
| Number of infants | 17 | 28 | |
| Hypertensive disease of pregnancy | 4 (24%) | 5 (18%) | 0.7 NS |
| Antepartum haemorrhage | 5 (29%) | 8 (29%) | 1.0 NS |
| Growth restriction | 1 (6%) | 0 (0%) | 0.3 NS |
| Poor flows | 5 (29%) | 3 (11%) | 0.2 NS |
| Antenatal steroids | 12 (71%) | 21 (75%) | 0.7 NS |
| Birthweight (g) (SD) | 1170 (343) | 1137 (332) | 0.8 NS |
| Gestation (weeks) (SD) | 28.7 (2.5) | 28.5 (2.0) | 0.8 NS |
| Male gender | 12 (71%) | 13 (46%) | 0.1 NS |
| Apgar score at 5 minutes (SD) | 7.1 (2.6) | 7.7 (1.3) | 0.3 NS |
| Patent ductus | 4 (24%) | 9 (32%) | 0.7 NS |
| Indomethacin given | 2 (12%) | 8 (29%) | 0.3 NS |
| Hyaline membrane disease | 6 (35%) | 16 (57%) | 0.2 NS |
| Fed before NEC | 17 (100%) | 26 (93%) | 0.5 NS |
| Only fed brest milk before NEC | 5 (29%) | 8 (29%) | 0.5 NS |
| Received plasma products before NEC | 14 (82%) | 27 (96%) | 0.1 NS |