Table 2

Demographic data, mean airway pressure, and number of infants with clinically significant reversed ductus venosus flow velocity (DVFV) during atrial contraction

No of CasesBirthweight (g)
Median (range)
Gestational age (weeks) Median (range)Mean airway pressure
(cm H2O) Median (range)
Significant reversed flow2-150
Study group162740 (1470–4230)35 (32–42)12 (7.5–16.5)16/16
Control group I
Subgroup IA503570 (2900–4685)40 (38–42)0/502-160
 Subgroup IB331290 (625–2100)31 (24–32)0/33
 Subgroup IC131905 (1415–2495)34 (32–35)0/13
Control group II11920 (625–1720)27 (24–31)9.3 (5–14.6)0/11
Control group III62595 (1180–3700)38 (30–40)6/6
  • 2-150 Group differences highly significant (study group and control group III vs other groups).

  • 2-160 During the first day of life, reversed DVFV during atrial systole was observed in 10 infants.

  • (Study group = neonates with PPHN, control group IA = healthy term neonates, control group IB = preterm neonates without PPHN, control group IC = preterm neonates with gestational age similar to that of study group, control group II = mechanically ventilated neonates with increased intrathoracic pressure but without PPHN, control group III = neonates with congenital heart defects and raised right atrial pressure).