Sensitivity analysis
| Assumption/varied to | Amount of difference | |
|---|---|---|
| a | Targeted programmes will miss 20% of SCDs targeted programmes will miss 10% of SCDs | Significant |
| b | Targeted programmes will miss 20% of SCDs targeted programmes will miss 1% of SCDs | Significant |
| c | Hospital overheads as modelled hospital overheads doubled | Not significant in populations > 25000 |
| d | Current cost of HPLC reagents cost of HPLC reagents halved | Significant |
| e | SCD births according to prevalence (no PND/TOP)/TOP in 20% | Significant |
| f | SCD births according to prevalence (no PND/TOP)/TOP in 10% | Not significant |
| g | Midwife selection will take 5 minutes midwife selection will take 10 minutes | Not significant |
| h | Midwife selection will take 5 minutes midwife selection will take 2 minutes | Not significant |
| i | Targeted programmes will incur extra clerical costs targeted programmes will not incur extra clerical costs | Not significant in populations > 25000 |
| j | Fixed costs as modelled fixed costs plus 20% and corresponding decrease in variable costs | Not significant |
| k | CMH hospitals overheads hospital overheads halved | Not significant |
| l | Targeted programmes will overestimate at-risk population by 20% targeted programmes will overestimate at-risk population by 40% | Not significant |
| m | Targeted programmes will overestimate at risk population by 20% targeted programmes will accurately estimate at-risk population | Not significant |