Table 3

Clinical outcomes

Clinical outcome Group TF Group C Mean difference p
Maximum serum conjugated bilirubin concentration (μmol/l)28 (23, 33)30 (23, 38)−2 (−12, 7)0.6
Maximum serum total bilirubin concentration (μmol/l)215 (201, 229)207 (190, 225)7.5 (−15, 30)0.5
Maximum serum alkaline phosphatase concentration (IU/l)975 (809, 1141)915 (782, 1048)60 (−149, 269)0.6
Maximum serum alanine transaminase concentration (IU/l)28 (21, 36)41 (25, 57)−13 (−30, 4)0.1
Phototherapy (hours)56 (44, 67)44 (32, 56)12 (−5, 28)0.2
Duration of jaundice (days)32 (26, 38)31 (24, 37)1.3 (−7.1, 9.7)0.5
Culture confirmed sepsis (episodes)0.5 (0.3, 0.7)1.2 (0.7, 1.7)−0.7 (−1.3, −0.2)0.043-151
C reactive protein >10 mg/l (days)2.2 (1, 3.4)4.3 (2.8, 5.8)−2.1 (−4, −0.1)<0.053-151
PN (days)20.6 (17, 25)32.1 (24, 39)−11.5 (−20, −3)0.013-151
Time to full enteral feeds (days)24.8 (21, 29)36.1 (28, 44)−11.2 (−19, −3)0.023-151
Time to full “sucking” feeds (days)61.5 (54, 69)77.1 (61, 93)−15.6 (−32, 1)0.08
Assisted ventilation (days)14.1 (11, 17.2)20.2 (12.2, 28.1)−6.1 (−14.8, 2.6)0.2
Supplemental oxygen (days)24 (17.4, 30.7)46.4 (29, 63.9)−22.4 (−41.5, −3.3)0.023-151
Hospital discharge (days)70.3 (61.8, 78.9)92.4 (73.9, 111)−22.1 (−42.1, −2.2)0.043-151
  • All outcomes are expressed as mean values with 95% confidence interval in parentheses.

  • 3-151 Denotes statistical significance.