Clinical outcome | Group TF | Group C | Mean difference | p |
Maximum serum conjugated bilirubin concentration (μmol/l) | 28 (23, 33) | 30 (23, 38) | −2 (−12, 7) | 0.6 |
Maximum serum total bilirubin concentration (μmol/l) | 215 (201, 229) | 207 (190, 225) | 7.5 (−15, 30) | 0.5 |
Maximum serum alkaline phosphatase concentration (IU/l) | 975 (809, 1141) | 915 (782, 1048) | 60 (−149, 269) | 0.6 |
Maximum serum alanine transaminase concentration (IU/l) | 28 (21, 36) | 41 (25, 57) | −13 (−30, 4) | 0.1 |
Phototherapy (hours) | 56 (44, 67) | 44 (32, 56) | 12 (−5, 28) | 0.2 |
Duration of jaundice (days) | 32 (26, 38) | 31 (24, 37) | 1.3 (−7.1, 9.7) | 0.5 |
Culture confirmed sepsis (episodes) | 0.5 (0.3, 0.7) | 1.2 (0.7, 1.7) | −0.7 (−1.3, −0.2) | 0.043-151 |
C reactive protein >10 mg/l (days) | 2.2 (1, 3.4) | 4.3 (2.8, 5.8) | −2.1 (−4, −0.1) | <0.053-151 |
PN (days) | 20.6 (17, 25) | 32.1 (24, 39) | −11.5 (−20, −3) | 0.013-151 |
Time to full enteral feeds (days) | 24.8 (21, 29) | 36.1 (28, 44) | −11.2 (−19, −3) | 0.023-151 |
Time to full “sucking” feeds (days) | 61.5 (54, 69) | 77.1 (61, 93) | −15.6 (−32, 1) | 0.08 |
Assisted ventilation (days) | 14.1 (11, 17.2) | 20.2 (12.2, 28.1) | −6.1 (−14.8, 2.6) | 0.2 |
Supplemental oxygen (days) | 24 (17.4, 30.7) | 46.4 (29, 63.9) | −22.4 (−41.5, −3.3) | 0.023-151 |
Hospital discharge (days) | 70.3 (61.8, 78.9) | 92.4 (73.9, 111) | −22.1 (−42.1, −2.2) | 0.043-151 |
All outcomes are expressed as mean values with 95% confidence interval in parentheses.
↵3-151 Denotes statistical significance.