Group | Month | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
9 | 12 | 13 | 24 | 36 | 48 | 60 | 61 | 72 | 84 | 96 | |
1 B: | |||||||||||
N | 50 | 57 | 56 | 48 | 49 | 45 | 46 | 20 | 20 | 18 | 16 |
% SP | 100 | 98.2 | 100 | 97.9 | 100 | 100 | 93.5 | 100 | 100 | 100 | 100 |
(95% CI) | 91.1-100 | 89.3-99.9 | 92.0-100 | 87.5-99.9 | 90.9-100 | 90.2-100 | 81.1-98.3 | 80.0-100 | 80.0-100 | 78.1-100 | 75.9-100 |
GMT (mIU/ml) | 327 | 165 | 3341 | 380 | 335 | 172 | 156 | 6682 | 1113 | 755 | 466 |
(95% CI) | 236-451 | 121-226 | 2264-4931 | 233-621 | 214-526 | 112-266 | 97-250 | 2996-14907 | 390-3182 | 306-1862 | 143-1510 |
1 NB: | |||||||||||
N | 26 | 25 | 22 | ||||||||
% SP | 100 | 100 | 95.5 | ||||||||
(95% CI) | 84.0-100 | 83.4-100 | 75.2-99.8 | ||||||||
GMT (mIU/ml) | 213 | 142 | 144 | ||||||||
(95% CI) | 128-356 | 84-240 | 80-258 | ||||||||
2 NB: | |||||||||||
N | 62 | 64 | 61 | 54 | 49 | 46 | 38 | 40 | 36 | 16 | |
% SP | 95.2 | 96.9 | 100 | 100 | 98.0 | 100 | 100.0 | 97.5 | 100.0 | 87.5 | |
(95% CI) | 85.7-98.8 | 88.2-99.5 | 92.6-100 | 91.7-100 | 87.8-99.9 | 90.4-100 | 88.6-100 | 85.3-99.9 | 88.0-100 | 60.4-97.8 | |
GMT (mIU/ml) | 211 | 161 | 4703 | 523 | 267 | 246 | 195 | 142 | 129 | 68 | |
(95% CI) | 153-290 | 115-225 | 3369-6565 | 336-813 | 175-407 | 167-360 | 130-293 | 92-221 | 88-189 | 33-141 | |
3 B: | |||||||||||
N | 55 | 56 | 52 | 50 | 46 | 48 | 21 | 19 | |||
% SP | 98.2 | 100 | 92.3 | 90.0 | 89.1 | 87.5 | 100.0 | 94.7 | |||
(95% CI) | 89.0-99.9 | 92.0-100 | 80.6-97.5 | 77.4-96.3 | 75.6-95.9 | 74.1-94.8 | 80.8-100 | 71.8-99.7 | |||
GMT (mIU/ml) | 507 | 295 | 86 | 80 | 59 | 42 | 2166 | 359 | |||
(95% CI) | 322-796 | 206-422 | 59-127 | 54-120 | 39-90 | 28-63 | 750-6258 | 116-1115 | |||
3 NB: | |||||||||||
N | 20 | ||||||||||
% SP | 85.0 | ||||||||||
(95% CI) | 61.1-96.0 | ||||||||||
GMT (mIU/ml) | 38 | ||||||||||
(95% CI) | 21-68 | ||||||||||
4 B: | |||||||||||
N | 58 | 59 | 54 | 51 | 46 | 45 | 21 | 16 | |||
% SP | 96.6 | 98.3 | 92.6 | 88.2 | 87.0 | 80.0 | 100.0 | 87.5 | |||
(95% CI) | 87.1-99.4 | 89.7-99.9 | 81.3-97.6 | 75.4-95.1 | 73.1-94.6 | 64.9-89.9 | 80.8-100 | 60.4-97.8 | |||
GMT (mIU/ml) | 317 | 180 | 70 | 82 | 63 | 38 | 4441 | 821 | |||
(95% CI) | 191-525 | 114-282 | 47-104 | 56-120 | 42-96 | 25-58 | 2043-9651 | 304-2215 | |||
4 NB: | |||||||||||
N | 19 | ||||||||||
% SP | 68.4 | ||||||||||
(95% CI) | 43.5-86.4 | ||||||||||
GMT (mIU/ml) | 27 | ||||||||||
(95% CI) | 14-51 |
% SP = seroprotection rate ( 10 mIU/ml); GMT = geometric mean titre.