Characteristics of trials included in the review: trials where dexamethasone has begun <36 hours of age
| Author | Year | Double blinded | Dose (mg/kg/day) | Course (days) | Start age | No of patients | Characteristics |
|---|---|---|---|---|---|---|---|
| Rastogiet al 30 | 1996 | Yes | 0.5 (3), 0.3 (3),1-150 0.2 (3), 0.1 (3) | 12 | <12 h | 64 | 700–1500 g; stratified 700–999 g, 1000–1249 g, 1250–1500g; surfactant, MV, 13% in dex and 47% in control received steroids |
| Shinwell et al 31 | 1996 | Yes | 0.5 (3) | 3 | <12 h | 248 | 500–2000 g; stratified 500–1000 g,1001–2000 g surfactant, MV, 27% in dex and 26% in control received steroids |
| Sander et al 32 | 1994 | Yes | 1 (1) | 1 | 12–18 h | 40 | <30 w GA; MV at 12–18 h; surfactant 10% in dex and 14% in control received steroids |
| Yeh et al 33 | 1990 | Yes | 1 (3), 0.5 (3), 0.25 (3), 0.1 (3) | 12 | <12 h | 60 | 700–1999 g; stratified <1000 g; 1001–1500 g; 3 excluded; MV |
| Tapia et al 39 | 1996 | Yes | 0.5 (3), 0.3 (3), 0.2 (3), 0.1 (3) | 12 | <36 h | 109 | 700–1600 g, MV; surfactant |
| Yehet al 38 | 1994 | Yes | 0.5 (7), 0.25 (7), 0.1 (7), 0.05 (7) | 28 | <12 h | 142 | <2000 g; MV |
↵1-150 Figures in parentheses indicate number of days. MV = mechanically ventilated; dex= dexamethasone.