Clinical features | With NEC (n=28) | Without NEC (n=112) |
---|---|---|
Gestational age (weeks) | 28.1 (26.3 to 30.4) | 29.0 (27.7 to 30.9) |
Birthweight (g) | 1095 (873 to 1348) | 1195 (960 to 1330) |
Sex (female:male) | 14 (50):14 (50) | 50 (45):62 (55) |
Inborn:outborn | 26 (93):2 (7) | 109 (97):3 (3) |
Antenatal corticosteroid treatment | 17 (61) | 78 (70) |
Mode of delivery | ||
Vaginal | 18 (64) | 43 (38) |
Caesarean section | 10 (36) | 66 (59) |
Ventouse | 0 (0) | 2 (2) |
Forceps | 0 (0) | 1 (1) |
Apgar scores | ||
1 min < 3 | 5 (18) | 14 (13) |
5 min < 3 | 1 (4) | 1 (1) |
First arterial blood gas after delivery | ||
pH | 7.37 (7.32 to 7.45) | 7.36 (7.30 to 7.44) |
Base excess | −2.4 (−5.0 to −0.80) | −2.6 (−5.6 to −0.9) |
Temperature on admission (°C) | 36.0 (35.8 to 36.8) | 36.2 (35.6 to 36.6) |
First venous haematocrit after delivery | 0.52 (0.47 to 0.55) | 0.51 (0.45 to 0.57) |
Lowest mean arterial blood pressure (mm Hg) | 27.5 (22.5 to 31.5) | 27 (22 to 32) |
Exchange transfusion | 1 (4) | 1 (1) |
Umbilical arterial catheterisation | 18 (64) | 62 (55) |
Umbilical venous catheterisation | 24 (86) | 90 (80) |
Aminophylline treatment | 20 (71) | 57 (51) |
Respiratory distress syndrome | ||
Stage 0-2 | 20 (71) | 86 (77) |
Stage 3-4 | 8 (29) | 26 (23) |
Periventricular haemorrhage | ||
Stage < 2 | 26 (93) | 94 (84) |
Stage 3-4 | 2 (7) | 18 (16) |
Patent ductus arteriosus | ||
Indomethacin closure | 15 (54) | 57 (51) |
Surgical ligation | 2 (7) | 3 (3) |
Age started on enteral feeds (days) | 6.5 (4 to 14.5) | 6 (4 to 9) |
Age received full enteral feeds (days) | 36 (23 to 61) | 26 (19 to 37) |
Type of milk feeds | ||
Breast | 3 (11) | 17 (15) |
Formula | 11 (39) | 50 (45) |
Mixed | 14 (50) | 45 (40) |
Stool culture (fungus: Gram (−): Gram (+)) | ||
Before prophylaxis | 0 (0):0 (0):5 (18) | 3 (3):8 (7):20 (18) |
Immediately after prophylaxis | 4 (14):6 (21):0 (0) | 13 (12):16 (14):3 (3) |
Four weeks after prophylaxis | 2 (7):6 (21):1 (4) | 3 (3):24 (21):1 (1) |
Duration of mechanical ventilation (days) | 9.5 (2 to 31) | 6.5 (3 to 16) |
Duration of O2 dependency (days) | 16 (3.5 to 47.5) | 10 (3 to 34) |
Duration of hospital stay (days)2-150 | 115 (90 to 144) | 81 (55 to 110) |
Died2-150 | 9 (32) | 15 (13) |
Continuous variables are expressed in median (interquartile ranges) and proportions in number of patients (%).
↵2-150 p<0.05.