Table 3

Heart rate, spontaneous respiratory rate, SaO2, tcPO2 and tcPCO2 within first 60 minutes after delivery of salbutamol aerosol

Device usedArea under the curve/60 min: adjusted mean (SEM)3-154
Heart rate (beats/min)Respiratory rate (breaths/min)SaO2(%)tcPO2
(mm Hg)
tcPCO2(mm Hg)
Study 1:
1 (MDI)168.6 (3.6)43.9 (1.2)95.9 (0.6)64.1 (0.8)32.2 (0.8)
2 (Jet)155.7 (3.6)42.7 (1.2)96.7 (0.6)61.3 (0.8)32.2 (0.8)
3 (Ultrasonic)168.8 (3.6)42.1 (1.2)95.8 (0 6)67.7 (0.8)30.6 (0.8)
F test p3-150 0.0231 0.5740.4610.00012 0.330
Study 2:
1 (MDI)156.7 (1.3)43.0 (1.2)94.8 (0.3)64.5 (0.5)30.4 (0.7)
2 (Jet)151.6 (1.9)41.0 (1.2)95.3 (0.3)62.3 (0.5)31.9 (0.7)
3 (Ultrasonic)168.8 (1.3)43 0 (1.2)95 4 (0.3)64.7 (0.5)28.7 (0.7)
F test p3-150 0.00013 0.2260.4770.0064 0.0145
• 3-154 Adjusted by covariance analysis with the pre-treatment values as covariance.

• 3-150 Analysis of covariance.

• Multiple pairwise comparison by pairwise student t test (adjusted for number of comparison):

• 1 MDI vs jet: p=0.018; Jet vs ultrasonic: p=0.016.

• 2 MDI vs jet: p=0.022; MDI vs ultrasonic: p=0.003; Jet vs ultrasonic: p=0.0001.

• 3 MDI vs jet: p=0.012; MDI vs ultrasonic: p=0.024; Jet vs ultrasonic: p=0.0001.

• 4 MDI vs jet: p=0.007; Jet vs ultrasonic: p=0.003.

• 5 Jet vs ultrasonic: p=0.004.