Table 1

Demographic characteristics and clinical course of infants studied

Case NoGestational age (weeks) Birthweight (g)Abdominal conditionAge when HFOV startedOutcome
1Female, 30, 1190NEC with gangrenous bowel and multiple  perforations; Enterobacter septicaemia and DICDay 14Extubated on day 30
2Male, 25, 600NEC with gangrenous bowel and multiple  perforationsDay 17Initial improvement; died on day 22 from  uncontrolled sepsis, renal failure and DIC
3Male, 25, 850NEC with perforation; Acinectobacter septicaemia  and peritonitisDay 63Extubated on day 90
4Female, 32, 1150Post-NEC ileal stricture resulting in acute bowel  obstruction and gangrene; Serratia septicaemiaDay 50Extubated 4 days later
5Male, 27, 1155Enterobacter septicaemia meningitis, and peritonitis;  normal intestinal tractDay 57Extubated 9 days later
6Male, 25, 890Massive hepatomegaly, ascites and liver failure  secondary to prolonged TPNDay 190Initial improvement; died on day 230 from  progressive liver failure
7Male, 34, 2275Gastroschisis with primary closure, complicated by  Enterobacter septicaemia, peritonitis and DICDay 4Initial improvement; died on day 9 from sepsis and  acute renal failure
8Male, 38, 3200Malrotation of small gut; necrosis and perforation of  stomach; partial gastrectomyDay 1Extubated on day 17
  • HFOV high frequency oscillatory ventilation; NEC necrotising enterocolitis; DIC disseminated intravascular coagulation; TPN total parenteral nutrition.