Effect of dexamethasone on absolute number of normoblasts that developed per plate (means (SEM))
| Normoblasts per plate | |||||
|---|---|---|---|---|---|
| Control | 10−9M DP | 10−8M DP | 10−7M DP | 10−6M DP | |
| 0.2 U/ml | 4188578 (1192983) | 4036535 (1057815) | 3734835 (650008) | 2118337 (680662) | 779261 (229384*) |
| 2 U/ml | 6235919 (1613897) | 8022497 (2956960) | 4751047 (1349938) | 3057200 (1245122) | 1482535 (438698*) |
| 20 U/ml | 6706827 (1873136) | 5585147 (314335) | 6386290 (1627679) | 3717635 (287624) | 1693370 (817661*) |
CD34+ progenitor cells were obtained from cord blood of five preterm infants and plated in quadruplicate in culture dishes in the presence of various concentrations of Epo and DP. After 14 days, cells were washed from culture dishes, and the absolute number of normoblasts per plate was calculated. Values are mean±SEM. * P < 0.005vs control.