PT  - JOURNAL ARTICLE
AU  - Fleiss, Noa
AU  - Schwabenbauer, Kathleen
AU  - Randis, Tara M
AU  - Polin, Richard A
TI  - What’s new in the management of neonatal early-onset sepsis?
AID  - 10.1136/archdischild-2021-323532
DP  - 2023 Jan 01
TA  - Archives of Disease in Childhood - Fetal and Neonatal Edition
PG  - 10--14
VI  - 108
IP  - 1
4099  - http://fn.bmj.com/content/108/1/10.short
4100  - http://fn.bmj.com/content/108/1/10.full
SO  - Arch Dis Child Fetal Neonatal Ed2023 Jan 01; 108
AB  - The expert guidelines highlighted in this review provide an evidence-based framework for approaching at-risk infants and allow for a more limited and standardised approach to antibiotic use. While these guidelines have significantly reduced antibiotic utilisation worldwide, optimally each unit would individualise their approach to early onset sepsis (EOS) based on the neonatal population they serve and available resources. As advancements in EOS research continue and limitations with sepsis prediction tools are addressed, it is inevitable that our risk stratification and management guidelines will become more precise.