TY - JOUR T1 - What’s new in the management of neonatal early-onset sepsis? JF - Archives of Disease in Childhood - Fetal and Neonatal Edition JO - Arch Dis Child Fetal Neonatal Ed SP - 10 LP - 14 DO - 10.1136/archdischild-2021-323532 VL - 108 IS - 1 AU - Noa Fleiss AU - Kathleen Schwabenbauer AU - Tara M Randis AU - Richard A Polin Y1 - 2023/01/01 UR - http://fn.bmj.com/content/108/1/10.abstract N2 - The expert guidelines highlighted in this review provide an evidence-based framework for approaching at-risk infants and allow for a more limited and standardised approach to antibiotic use. While these guidelines have significantly reduced antibiotic utilisation worldwide, optimally each unit would individualise their approach to early onset sepsis (EOS) based on the neonatal population they serve and available resources. As advancements in EOS research continue and limitations with sepsis prediction tools are addressed, it is inevitable that our risk stratification and management guidelines will become more precise. ER -