PT - JOURNAL ARTICLE AU - Sophie Jansen AU - Romy J M Berkhout AU - Arjan B te Pas AU - Sylke J Steggerda AU - Linda S de Vries AU - Nicoline Schalij-Delfos AU - Alieke van der Hoeven AU - Enrico Lopriore AU - Vincent Bekker TI - Comparison of neonatal morbidity and mortality between single-room and open-bay care: a retrospective cohort study AID - 10.1136/archdischild-2021-323310 DP - 2022 Nov 01 TA - Archives of Disease in Childhood - Fetal and Neonatal Edition PG - 611--616 VI - 107 IP - 6 4099 - http://fn.bmj.com/content/107/6/611.short 4100 - http://fn.bmj.com/content/107/6/611.full SO - Arch Dis Child Fetal Neonatal Ed2022 Nov 01; 107 AB - Objective In response to the increasing focus on family-centred care, neonatal intensive care unit (NICU) environments have gradually shifted towards the single-room design. However, the assumed benefits of this emerging design remain a subject of debate. Our goal was to evaluate the impact of single-room versus open-bay care on the risk of neonatal morbidity and mortality in preterm neonates.Design Retrospective cohort study.Setting Level III NICU.Patients Neonates born <32 weeks’ gestation between 15 May 2015 and 15 May 2019.Main outcome measures Mortality and morbidities of a cohort of neonates admitted to a new, single-room unit (SRU) were compared with a historical cohort of neonates admitted to an open-bay unit (OBU). Group differences were evaluated and multivariable logistic regression analyses were performed.Results Three-hundred and fifty-six and 343 neonates were admitted to the SRU and OBU, respectively. No difference in neonatal morbidities and mortality were observed between cohorts (bronchopulmonary dysplasia: OR 1.08, 95% CI 0.73 to 1.58, p=0.44; retinopathy of the prematurity stage ≥2: OR 1.36, 95% CI 0.84 to 2.22, p=0.10; intraventricular haemorrhage: OR 0.89, 95% CI 0.59 to 1.34, p=0.86; mortality: OR 1.55, 95% CI 0.75 to 3.20, p=0.28). In adjusted regression models, single-room care was independently associated with a decreased risk of symptomatic patent ductus arteriosus (adjusted OR 0.54, 95% CI 0.31 to 0.95). No independent association between single-room care and any of the other investigated outcomes was observed.Conclusions Implementation of single-rooms in our NICU did not lead to a significant reduction in neonatal morbidity and mortality outcomes.Data are available upon request from the corresponding author.