TY - JOUR T1 - Current evidence for prenatal and postnatal corticosteroids in preterm infants JF - Archives of Disease in Childhood - Fetal and Neonatal Edition JO - Arch Dis Child Fetal Neonatal Ed SP - 121 LP - 125 DO - 10.1136/archdischild-2020-319706 VL - 107 IS - 2 AU - Eric S Shinwell AU - Polina Gurevitz AU - Igor Portnov Y1 - 2022/03/01 UR - http://fn.bmj.com/content/107/2/121.abstract N2 - Antenatal corticosteroids undoubtedly save many lives and improve the quality of many others. However, the currently accepted dosage schedule has been in place since 1972, and recent studies have suggested that beneficial effects may be seen with less. Most but not all studies of long-term outcome show no adverse effects. The use of antenatal corticosteroids in women with COVID-19 raises important questions regarding potential risks and benefits. However, currently, most authorities recommend continuing according to published guidelines. With regard to postnatal corticosteroids, alternatives to systemic dexamethasone, the somewhat tainted standard of care, show promise in preventing bronchopulmonary dysplasia without adverse effects. Systemic hydrocortisone and inhaled corticosteroids are of note. The mixture of surfactant and corticosteroids deserves particular attention in the coming years.Data are available in a public, open access repository. ER -