TY - JOUR T1 - Decision to extubate extremely preterm infants: art, science or gamble? JF - Archives of Disease in Childhood - Fetal and Neonatal Edition JO - Arch Dis Child Fetal Neonatal Ed SP - 105 LP - 112 DO - 10.1136/archdischild-2020-321282 VL - 107 IS - 1 AU - Wissam Shalish AU - Martin Keszler AU - Peter G Davis AU - Guilherme M Sant’Anna Y1 - 2022/01/01 UR - http://fn.bmj.com/content/107/1/105.abstract N2 - In the modern era of neonatology, mechanical ventilation has been restricted to a smaller and more immature population of extremely preterm infants. Given the adverse outcomes associated with mechanical ventilation, every effort is made to extubate these infants as early as possible. However, the scientific basis for determining extubation readiness remains imprecise and primarily guided by clinical judgement, which is highly variable and subjective. In the absence of accurate tools to assess extubation readiness, many infants fail their extubation attempt and require reintubation, which also increases complications. Recent advances in the field have led to unravelling some of the complexities surrounding extubation in this population. This review aims to synthesise the available knowledge and provide a more evidence-based approach towards the reporting of extubation outcomes and assessment of extubation readiness in extremely preterm infants.Data sharing not applicable as no datasets generated and/or analysed for this study. ER -