PT - JOURNAL ARTICLE AU - Anne R Synnes AU - Julie Petrie AU - Ruth E Grunau AU - Paige Church AU - Edmond Kelly AU - Diane Moddemann AU - Xiang Ye AU - Shoo K Lee AU - Karel O'Brien AU - Canadian Neonatal Network Investigators ED - , TI - Family integrated care: very preterm neurodevelopmental outcomes at 18 months AID - 10.1136/archdischild-2020-321055 DP - 2022 Jan 01 TA - Archives of Disease in Childhood - Fetal and Neonatal Edition PG - 76--81 VI - 107 IP - 1 4099 - http://fn.bmj.com/content/107/1/76.short 4100 - http://fn.bmj.com/content/107/1/76.full SO - Arch Dis Child Fetal Neonatal Ed2022 Jan 01; 107 AB - Objective To examine whether the family integrated care (FICare) programme, a multifaceted approach which enables parents to be engaged as primary caregivers in the neonatal intensive care unit, impacts infant neurodevelopment and growth at 18 months’ corrected age.Design/Methods Prospective cohort study of infants born <29 weeks’ gestational age (GA) who participated in the FICare cluster randomised control trial (cRCT) and were assessed in the Canadian Neonatal Follow-Up Network (CNFUN). The primary outcome measure, Cognitive or Language composite score <85 on the Bayley-III, was compared between FICare exposed and routine care children using logistic regression, adjusted for potential confounders and employing generalised estimation equations to account for clustering of infants within sites.Results Of 756 infants <29 weeks’ GA in the FICare cRCT, 505 were enrolled in CNFUN and 455 were assessed (238 FICare, 217 control). Compared with controls, FICare infants had significantly higher incidence of intraventricular haemorrhage (IVH) (19.5% vs 11.7%, p=0.024) and higher proportion of employed mothers (76.6% vs 73.6%, p=0.043). There was no significant difference in the odds of the primary outcome (adjusted OR: 0.92 (0.59 to 1.42) FiCare vs Control) on multivariable analyses adjusted for GA, IVH and maternal employment. However, Bayley-III Motor scores (adjusted difference in mean (95% CI) 3.87 (1.22 to 6.53) and body mass index 0.67 (0.36 to 0.99) were higher in the FICare group.Conclusions Very preterm infants exposed to FICare had no significant difference in incidence of cognitive or language delay but had better motor development.Trial registration number Participants in this cohort study were previously enrolled in a registered trial: NCT01852695 No data are available according to network data sharing agreements.