@article {Synnes76, author = {Anne R Synnes and Julie Petrie and Ruth E Grunau and Paige Church and Edmond Kelly and Diane Moddemann and Xiang Ye and Shoo K Lee and Karel O{\textquoteright}Brien and Canadian Neonatal Network Investigators}, editor = {, and , and Kanungo, Jaideep and Ting, Joseph and Mehrem, Ayman Abou and Alvaro, Ruben and Adie, Mohammad and Silva, Orlando Da and Shah, Prakesh S and Ng, Eugene and Drolet, Christine and Piedboeuf, Bruno and Afifi, Jehier and , and Pillay, Thevanisha and Synnes, Anne and Grunau, Ruth and Zwicker, Jill and Hendson, Leonora and Moddemann, Diane and Cabo, Cecilia de and Nwaesei, Chukwuma and Coughlin, Kevin and Kelly, Edmond and Church, Paige and Banihani, Rudaina and Luu, Thuy Mai and B{\'e}langer, Sylvie and Afifi, Jehier}, title = {Family integrated care: very preterm neurodevelopmental outcomes at 18 months}, volume = {107}, number = {1}, pages = {76--81}, year = {2022}, doi = {10.1136/archdischild-2020-321055}, publisher = {BMJ Publishing Group}, abstract = {Objective To examine whether the family integrated care (FICare) programme, a multifaceted approach which enables parents to be engaged as primary caregivers in the neonatal intensive care unit, impacts infant neurodevelopment and growth at 18 months{\textquoteright} corrected age.Design/Methods Prospective cohort study of infants born \<29 weeks{\textquoteright} gestational age (GA) who participated in the FICare cluster randomised control trial (cRCT) and were assessed in the Canadian Neonatal Follow-Up Network (CNFUN). The primary outcome measure, Cognitive or Language composite score \<85 on the Bayley-III, was compared between FICare exposed and routine care children using logistic regression, adjusted for potential confounders and employing generalised estimation equations to account for clustering of infants within sites.Results Of 756 infants \<29 weeks{\textquoteright} GA in the FICare cRCT, 505 were enrolled in CNFUN and 455 were assessed (238 FICare, 217 control). Compared with controls, FICare infants had significantly higher incidence of intraventricular haemorrhage (IVH) (19.5\% vs 11.7\%, p=0.024) and higher proportion of employed mothers (76.6\% vs 73.6\%, p=0.043). There was no significant difference in the odds of the primary outcome (adjusted OR: 0.92 (0.59 to 1.42) FiCare vs Control) on multivariable analyses adjusted for GA, IVH and maternal employment. However, Bayley-III Motor scores (adjusted difference in mean (95\% CI) 3.87 (1.22 to 6.53) and body mass index 0.67 (0.36 to 0.99) were higher in the FICare group.Conclusions Very preterm infants exposed to FICare had no significant difference in incidence of cognitive or language delay but had better motor development.Trial registration number Participants in this cohort study were previously enrolled in a registered trial: NCT01852695 No data are available according to network data sharing agreements.}, issn = {1359-2998}, URL = {https://fn.bmj.com/content/107/1/76}, eprint = {https://fn.bmj.com/content/107/1/76.full.pdf}, journal = {Archives of Disease in Childhood - Fetal and Neonatal Edition} }