PT - JOURNAL ARTICLE AU - Cavallin, Francesco AU - Doglioni, Nicoletta AU - Allodi, Alessandra AU - Battajon, Nadia AU - Vedovato, Stefania AU - Capasso, Letizia AU - Gitto, Eloisa AU - Laforgia, Nicola AU - Paviotti, Giulia AU - Capretti, Maria Grazia AU - Gizzi, Camilla AU - Villani, Paolo Ernesto AU - Biban, Paolo AU - Pratesi, Simone AU - Lista, Gianluca AU - Ciralli, Fabrizio AU - Soffiati, Massimo AU - Staffler, Alex AU - Baraldi, Eugenio AU - Trevisanuto, Daniele ED - , TI - Thermal management with and without servo-controlled system in preterm infants immediately after birth: a multicentre, randomised controlled study AID - 10.1136/archdischild-2020-320567 DP - 2021 Nov 01 TA - Archives of Disease in Childhood - Fetal and Neonatal Edition PG - 572--577 VI - 106 IP - 6 4099 - http://fn.bmj.com/content/106/6/572.short 4100 - http://fn.bmj.com/content/106/6/572.full SO - Arch Dis Child Fetal Neonatal Ed2021 Nov 01; 106 AB - Background The thermal servo-controlled systems are routinely used in neonatal intensive care units (NICUs) to accurately manage patient temperature, but their role during the immediate postnatal phase has not been previously assessed.Objective To compare two modalities of thermal management (with and without the use of a servo-controlled system) immediately after birth.Study design and setting Multicentre, unblinded, randomised trial conducted 15 Italian tertiary hospitals.Participants Infants with estimated birth weight <1500 g and/or gestational age <30+6 weeks.Intervention Thermal management with or without a thermal servo-controlled system during stabilisation in the delivery room.Primary outcome Proportion of normothermia at NICU admission (axillary temperature 36.5°C–37.5°C).Results At NICU admission, normothermia was achieved in 89/225 neonates (39.6%) with the thermal servo-controlled system and 95/225 neonates (42.2%) without the thermal servo-controlled system (risk ratio 0.94, 95% CI 0.75 to 1.17). Thermal servo-controlled system was associated with increased mild hypothermia (36°C–36.4°C) (risk ratio 1.48, 95% CI 1.09 to 2.01).Conclusions In very low birthweight infants, thermal management with the servo-controlled system conferred no advantage in maintaining normothermia at NICU admission, while it was associated with increased mild hypothermia. Thermal management of preterm infants immediately after birth remains a challenge.Trial registration number NCT03844204 Data are available on reasonable request. Data are available on reasonable request to the corresponding author.