RT Journal Article SR Electronic T1 Family integrated care: very preterm neurodevelopmental outcomes at 18 months JF Archives of Disease in Childhood - Fetal and Neonatal Edition JO Arch Dis Child Fetal Neonatal Ed FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP fetalneonatal-2020-321055 DO 10.1136/archdischild-2020-321055 A1 Anne R Synnes A1 Julie Petrie A1 Ruth E Grunau A1 Paige Church A1 Edmond Kelly A1 Diane Moddemann A1 Xiang Ye A1 Shoo K Lee A1 Karel O'Brien A1 Canadian Neonatal Network Investigators A1 , YR 2021 UL http://fn.bmj.com/content/early/2021/06/17/archdischild-2020-321055.abstract AB Objective To examine whether the family integrated care (FICare) programme, a multifaceted approach which enables parents to be engaged as primary caregivers in the neonatal intensive care unit, impacts infant neurodevelopment and growth at 18 months’ corrected age.Design/Methods Prospective cohort study of infants born <29 weeks’ gestational age (GA) who participated in the FICare cluster randomised control trial (cRCT) and were assessed in the Canadian Neonatal Follow-Up Network (CNFUN). The primary outcome measure, Cognitive or Language composite score <85 on the Bayley-III, was compared between FICare exposed and routine care children using logistic regression, adjusted for potential confounders and employing generalised estimation equations to account for clustering of infants within sites.Results Of 756 infants <29 weeks’ GA in the FICare cRCT, 505 were enrolled in CNFUN and 455 were assessed (238 FICare, 217 control). Compared with controls, FICare infants had significantly higher incidence of intraventricular haemorrhage (IVH) (19.5% vs 11.7%, p=0.024) and higher proportion of employed mothers (76.6% vs 73.6%, p=0.043). There was no significant difference in the odds of the primary outcome (adjusted OR: 0.92 (0.59 to 1.42) FiCare vs Control) on multivariable analyses adjusted for GA, IVH and maternal employment. However, Bayley-III Motor scores (adjusted difference in mean (95% CI) 3.87 (1.22 to 6.53) and body mass index 0.67 (0.36 to 0.99) were higher in the FICare group.Conclusions Very preterm infants exposed to FICare had no significant difference in incidence of cognitive or language delay but had better motor development.Trial registration number Participants in this cohort study were previously enrolled in a registered trial: NCT01852695 No data are available according to network data sharing agreements.