TY - JOUR T1 - Waveform capnography in neonatal intensive care: is it unreliable? JF - Archives of Disease in Childhood - Fetal and Neonatal Edition JO - Arch Dis Child Fetal Neonatal Ed SP - 228 LP - 228 DO - 10.1136/archdischild-2020-321007 VL - 106 IS - 2 AU - Theodore Dassios AU - Emma E Williams AU - Anne Greenough Y1 - 2021/03/01 UR - http://fn.bmj.com/content/106/2/228.abstract N2 - We read with interest the study by Scrivens et al,1 which evaluated the evidence on the applicability of waveform capnography in neonatal intensive care. While in principle we agree that currently there is insufficient evidence to support the routine application of tidal capnography in clinical practice, we would like to describe some more recent developments that could inform future clinical practice and research.The authors highlight that end-tidal carbon dioxide (ET-CO2) values under-read the true arterial CO2 and that agreement between arterial and ET-CO2 decreases with increasing severity of lung disease, suggesting a decreased reliability of the method in those babies who require the closest monitoring. The ET-CO2 value, … ER -