TY - JOUR T1 - Off-label use of paracetamol in managing patent ductus arteriosus across neonatal intensive care units in the UK JF - Archives of Disease in Childhood - Fetal and Neonatal Edition JO - Arch Dis Child Fetal Neonatal Ed SP - 113 LP - 114 DO - 10.1136/archdischild-2020-320207 VL - 106 IS - 1 AU - Arindam Mukherjee AU - Vishal Jadhav AU - Anupam Gupta Y1 - 2021/01/01 UR - http://fn.bmj.com/content/106/1/113.abstract N2 - A haemodynamically significant patent ductus arteriosus (hsPDA) contributes significantly to mortality and morbidity in infants born earlier than 28 weeks’ gestation. Intravenous ibuprofen is the only licensed medication for medical management of patent ductus arteriosus (PDA) in the UK. It has its own side effects. There is emerging evidence to suggest that paracetamol may be a safer substitute to ibuprofen.We carried out a national telephone survey to ascertain the majority response on off-label use of paracetamol and explore areas of possible research in its use for managing hsPDA. The survey was conducted across 63 level 3 neonatal intensive care units … ER -