RT Journal Article SR Electronic T1 Mask versus nasal prong leak and intermittent hypoxia during continuous positive airway pressure in very preterm infants JF Archives of Disease in Childhood - Fetal and Neonatal Edition JO Arch Dis Child Fetal Neonatal Ed FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP 81 OP 83 DO 10.1136/archdischild-2020-319092 VO 106 IS 1 A1 Christian F Poets A1 Kathleen Lim A1 Andrew Marshall A1 Hamish Jackson A1 Timothy J Gale A1 Peter A Dargaville YR 2021 UL http://fn.bmj.com/content/106/1/81.abstract AB Background Nasal continuous positive airway pressure (NCPAP) can be applied via binasal prongs or nasal masks; both may be associated with air leak and intermittent hypoxia. We investigated whether the latter is more frequent with nasal masks or prongs.Methods Continuous 24 hours recordings of inspired oxygen fraction (FiO2), pulse rate, respiratory rate, pulse oximeter saturation (SpO2) and CPAP level were made in preterm infants with respiratory insufficiency (n=20) managed on CPAP in the NICU at the Royal Hobart Hospital. As part of routine care, nasal interfaces were alternated 4-hourly between mask and prongs. In each recording, the first two segments containing at least 3 hours of artefact-free signal for each interface were selected. Recordings were analysed for episodes with hypoxaemia (SpO2 <80% for ≥10 s) and bradycardia (pulse rate <80/min for ≥4 s) and for episodes of pressure loss at the nasal interface. Data were compared using Wilcoxon-matched pairs test and are reported as median (IQR).Results Infants had a gestational age at birth of 26 (25-27) weeks and postnatal age of 17 (14–24) days. There was no difference in %time with interface leak between prong and mask (0.9 (0–8)% vs 1.1 (0–18)%, p=0.82), %time with SpO2 <80% (0.15 (0–1.2)% vs 0.06 (0–0.8)%, p=0.74) or heart rate <80/min (0.03 (0–0.2)% vs 0 (0–0.2)%, p=0.64). Three infants had interface leak for >10% of the time with prongs and 5 with the mask.Conclusion Both interfaces resulted in a similarly stable provision of positive airway pressure, and there was also no difference in the occurrence of intermittent hypoxia.