@article {Larsenfetalneonatal-2020-319767, author = {Petra P Larsen and Andreas M{\"u}ller and Wolf A Lagr{\`e}ze and Frank G Holz and Andreas Stahl and Tim U Krohne}, editor = {, and , and Breu{\ss}, Helge and Rieckehr, Nadja and Engelmann, Katrin and Hecker, Jacqueline and Gabel-Pfisterer, Ameli and Koutsonas, Antonios and Walter, Peter and Krohne, Tim U and Li, Jeany Q and Liegl, Raffael and Daniel, Moritz and Goos, Daniela and Lorenz, Birgit and Mais, Christine and Bemme, Sebastian and Feltgen, Nicolas and Hoerauf, Hans and Br{\"u}nder, Marie-Christine and Stahl, Andreas and Knospe, Volker and Wagenfeld, Lars and Skevas, Christos and Spitzer, Martin and Pielen, Amelie and Eter, Nicole and Glitz, Barbara and M{\"u}ller, Viktoria C and Barth, Teresa and Bartz-Schmidt, Karl Ulrich and S{\"u}sskind, Daniela and Hagemann, Ulrike and Aisenbrey, Sabine and Macher, Thomas}, title = {Incidence of retinopathy of prematurity in Germany: evaluation of current screening criteria}, elocation-id = {fetalneonatal-2020-319767}, year = {2020}, doi = {10.1136/archdischild-2020-319767}, publisher = {BMJ Publishing Group}, abstract = {Objective To evaluate current screening criteria for retinopathy of prematurity (ROP) by investigating the incidence of ROP requiring treatment in infants with gestational age (GA) >=30 weeks or postmenstrual age (PMA) \<32 weeks in Germany.Methods Three patient databases were analysed, that is, the German Quality Assurance Procedure in Neonatology (years 2011{\textendash}2017; n=52 461 infants screened for ROP, 1505 infants treated for ROP), the German Retina.net ROP Registry (years 2011{\textendash}2018; n=281 treated infants) and the ROP screening programme of two German university hospitals (years 2012{\textendash}2016; n=837 screened infants).Results In the analysed cohorts, infants with GA >=30 weeks represented 33.1\%{\textendash}38.5\% of the screening populations but only 1.40\%{\textendash}1.42\% of the cases requiring ROP treatment. In a cohort of 281 infants treated for ROP, all 4 infants with GA >=30 weeks had additional risk factors for ROP including prolonged oxygen supplementation and/or significant comorbidities. Five infants (1.8\%) were treated at 32 weeks PMA and none at PMA \<32 weeks.Conclusions In the investigated cohorts, preterm infants with GA >=30 weeks carried a very low or no risk for developing treatment-requiring ROP unless additional risk factors were present, and no treatment was performed earlier than 32 weeks PMA. These findings are of relevance for the ongoing re-evaluation of ROP screening criteria.}, issn = {1359-2998}, URL = {https://fn.bmj.com/content/early/2020/09/27/archdischild-2020-319767}, eprint = {https://fn.bmj.com/content/early/2020/09/27/archdischild-2020-319767.full.pdf}, journal = {Archives of Disease in Childhood - Fetal and Neonatal Edition} }