TY - JOUR T1 - Duct-dependent congenital heart disease in very preterm infants JF - Archives of Disease in Childhood - Fetal and Neonatal Edition JO - Arch Dis Child Fetal Neonatal Ed DO - 10.1136/archdischild-2019-317742 SP - fetalneonatal-2019-317742 AU - Kristin N Ferguson AU - Sheryle R Rogerson AU - Peter G Davis AU - Bryn O Jones AU - Darren Hutchinson AU - Rod W Hunt AU - Brett J Manley Y1 - 2020/03/13 UR - http://fn.bmj.com/content/early/2020/03/13/archdischild-2019-317742.abstract N2 - Duct-dependent congenital heart disease (DD-CHD) encompasses severe cardiac malformations that rely on postnatal patency of the ductus arteriosus to maintain adequate circulation. Prostaglandin E1 (PGE1) is most commonly used to maintain patency of the ductus arteriosus. Both prematurity (birth before 37 weeks’ gestation) and low birth weight (<2500 g) are associated with poor prognosis for infants with congenital heart disease.1 2 There are few reports of the outcomes of very preterm infants born at <32 weeks’ gestation with DD-CHD treated with PGE1. We aimed to describe the mortality and morbidity of this relatively rare but high-risk group.A review was undertaken of the medical records of very preterm infants with DD-CHD treated with PGE1 born at The Royal Women’s Hospital, Melbourne, Australia, between January 2006 and December 2016. Infants were excluded if … ER -