@article {Bethell178, author = {George Stephen Bethell and Anna-May Long and Marian Knight and Nigel J Hall}, editor = {, and , and Jones, Abigail and Aslam, Adil and Mortell, Alan and Mccabe, Amanda and Ross, Andrew and Harris, Anna and Lawson, Anne and Kelay, Arun and Abhyankar, Aruna and Rajimwale, Ashok and Saeed, Atif and Eradi, Bala and Sharif, Baqer and Maccormack, Brian and Pardy, Caroline and Ridd, Catherine and Jones, Ceri and Jones, Ceri and Driver, Chris and Parsons, Chris and Kwok, Chun-sui and Rees, Clare and Skerritt, Clare and Aronson, Dan and Marshall, David and Deacy, Dawn and Banerjee, Debasish and Caluwe, Diane De and Kufeji, Dorothy and Cusick, Eleri and O{\textquoteright}connor, Elizabeth and Bough, Georgina and Murthi, Govind and Patel, Hetal and Jones, Ian and Sugarman, Ian and Njere, Ike and Jester, Ingo and Durell, Jonathan and Cao, Kevin and Elmalik, Khalid and Tullie, Lucinda and Kakade, Madhavi and Haneef, Maryam and Matcovici, Melania and Dawrant, Michael and Horridue, Michelle and Soares-oliveira, Miguel and Doyle, Miriam and Shalaby, Mohamed and Allan, Morven and Burdell, Oliver and Charlesworth, Paul and Johnson, Paul and Hill, Richard and Cresner, Rosie and Craigie, Ross and Gupta, Samir and Motiwale, Sandeep and Besarovic, Sanja and Paramalingam, Saravanakumar and Marven, Sean and Patel, Shailesh and Sharif, Shazia and Naqvi, Shehryer and Clarke, Simon and Kenny, Simon and Giuliani, Stefano and Payne, Susan and Tyraskis, Thanos and Tsang, Thomas and Bradnock, Tim and Calvert, William and Patel, Yatin}, title = {Congenital duodenal obstruction in the UK: a population-based study}, volume = {105}, number = {2}, pages = {178--183}, year = {2020}, doi = {10.1136/archdischild-2019-317085}, publisher = {BMJ Publishing Group}, abstract = {Objective Congenital duodenal obstruction (CDO) comprising duodenal atresia or stenosis is a rare congenital anomaly requiring surgical correction in early life. Identification of variation in surgical and postoperative practice in previous studies has been limited by small sample sizes. This study aimed to prospectively estimate the incidence of CDO in the UK, and report current management strategies and short-term outcomes.Design Prospective population-based, observational study for 12 months from March 2016.Setting Specialist neonatal surgical units in the UK.Main outcome measures Incidence of CDO, associated anomalies and short-term outcomes.Results In total, 110 cases were identified and data forms were returned for 103 infants giving an estimated incidence of 1.22 cases per 10 000 (95\% CI 1.01 to 1.49) live births. Overall, 59\% of cases were suspected antenatally and associated anomalies were seen in 69\%. Operative repair was carried out mostly by duodenoduodenostomy (76\%) followed by duodenojejunostomy (15\%). Postoperative feeding practice varied with 42\% having a trans-anastomotic tube placed and 88\% receiving parenteral nutrition. Re-operation rate related to the initial procedure was 3\% within 28 days. Two infants died within 28 days of operation from unrelated causes.Conclusion This population-based study of CDO has shown that the majority of infants have associated anomalies. There is variation in postoperative feeding strategies which represent opportunities to explore the effects of these on outcome and potentially standardise approach. Short-term outcomes are generally good.}, issn = {1359-2998}, URL = {https://fn.bmj.com/content/105/2/178}, eprint = {https://fn.bmj.com/content/105/2/178.full.pdf}, journal = {Archives of Disease in Childhood - Fetal and Neonatal Edition} }