PT  - JOURNAL ARTICLE
AU  - Hannah Ellin Knight
AU  - Sam J Oddie
AU  - Katie L Harron
AU  - Harriet K Aughey
AU  - Jan H van der Meulen
AU  - Ipek Gurol-Urganci
AU  - David A Cromwell
TI  - Establishing a composite neonatal adverse outcome indicator using English hospital administrative data
AID  - 10.1136/archdischild-2018-315147
DP  - 2019 Sep 01
TA  - Archives of Disease in Childhood - Fetal and Neonatal Edition
PG  - F502--F509
VI  - 104
IP  - 5
4099  - http://fn.bmj.com/content/104/5/F502.short
4100  - http://fn.bmj.com/content/104/5/F502.full
SO  - Arch Dis Child Fetal Neonatal Ed2019 Sep 01; 104
AB  - Objective We adapted a composite neonatal adverse outcome indicator (NAOI), originally derived in Australia, and assessed its feasibility and validity as an outcome indicator in English administrative hospital data.Design We used Hospital Episode Statistics (HES) data containing information infants born in the English National Health Service (NHS) between 1 April 2014 and 31 March 2015. The Australian NAOI was mapped to diagnoses and procedure codes used within HES and modified to reflect data quality and neonatal health concerns in England. To investigate the concurrent validity of the English NAOI (E-NAOI), rates of NAOI components were compared with population-based studies. To investigate the predictive validity of the E-NAOI, rates of readmission and death in the first year of life were calculated for infants with and without E-NAOI components.Results The analysis included 484 007 (81%) of the 600 963 eligible babies born during the timeframe. 114/148 NHS trusts passed data quality checks and were included in the analysis. The modified E-NAOI included 23 components (16 diagnoses and 7 procedures). Among liveborn infants, 5.4% had at least one E-NAOI component recorded before discharge. Among newborns discharged alive, the E-NAOI was associated with a significantly higher risk of death (0.81% vs 0.05%; p<0.001) and overnight hospital readmission (15.7% vs 7.1%; p<0.001) in the first year of life.Conclusions A composite NAOI can be derived from English hospital administrative data. This E-NAOI demonstrates good concurrent and predictive validity in the first year of life. It is a cost-effective way to monitor neonatal outcomes.