TY - JOUR T1 - T-piece versus self-inflating bag ventilation in preterm neonates at birth JF - Archives of Disease in Childhood - Fetal and Neonatal Edition JO - Arch Dis Child Fetal Neonatal Ed SP - F49 LP - F55 DO - 10.1136/archdischild-2016-312360 VL - 103 IS - 1 AU - Ruth Guinsburg AU - Maria Fernanda Branco de Almeida AU - Junia Sampel de Castro AU - Walusa Assad Gonçalves-Ferri AU - Patricia Franco Marques AU - Jamil Pedro Siqueira Caldas AU - Vera Lucia Jornada Krebs AU - Ligia Maria Suppo de Souza Rugolo AU - João Henrique Carvalho Leme de Almeida AU - Jorge Hecker Luz AU - Renato S Procianoy AU - José Luiz Muniz Bandeira Duarte AU - Marcia Gomes Penido AU - Daniela Marques de Lima Mota Ferreira AU - Navantino Alves Filho AU - Edna Maria de Albuquerque Diniz AU - Juliana Paula Santos AU - Ana Lucia Acquesta AU - Cristina Nunes dos Santos AU - Maria Rafaela Conde Gonzalez AU - Regina PG Vieira Cavalcanti da Silva AU - Jucile Meneses AU - José Maria de Andrade Lopes AU - Franciscó Eulógio Martinez Y1 - 2018/01/01 UR - http://fn.bmj.com/content/103/1/F49.abstract N2 - Objective To verify whether the use of the T-piece resuscitator compared with the self-inflating bag in preterm infants ventilated at birth modifies survival to hospital discharge without major morbidities.Design Pragmatic prospective cohort study.Setting 20 Brazilian university hospitals of Brazilian Network on Neonatal Research. Patients were 1962 inborn infants in 2014–2015 ventilated at birth with 23–33’ weeks gestation and birth weight 400–1499 g without malformations. Patients transferred until the 27th day after birth were excluded.Interventions Positive pressure ventilation at birth with T-piece resuscitator or self-inflating bag without positive end expiratory pressure valve. Intervention with ventilation followed the Brazilian Society of Pediatrics guidelines. The choice of the equipment was at the neonatologist’s discretion in each delivery. The main outcome measures were survival to hospital discharge without bronchopulmonary dysplasia, severe peri-intraventricular haemorrhage and periventricular leucomalacia. Logistic regression adjusted for confounding variables was applied for main outcome.Results 1456 (74%) were only ventilated with T-piece resuscitator and 506 (26%) with the self-inflating bag. The characteristics of those ventilated with T-Piece resuscitator versus self-inflating bag were birth weight 969 ± 277 vs 941 ± 279 g, gestational age 28.2±2.5 vs 27.8±2.7 weeks and survival to hospital discharge without major morbidities 47% vs 35%. Logistic regression adjusted for maternal characteristics, obstetric and neonatal morbidities showed that the T-piece resuscitator increased the chance of survival to hospital discharge without major morbidities (OR=1.38; 95% CI 1.06 to 1.80; Hosmer-Lemeshow goodness of fit: 0.695).Conclusion This study is the first that highlights the effectiveness of T-piece resuscitator ventilation in improving relevant outcomes in preterm neonates. ER -