PT - JOURNAL ARTICLE AU - R Carbajal AU - E Courtois AU - M Eriksson AU - H Lagercrantz AU - EM Boyle TI - PC.77 Sedation and analgesia for neonates in NICUs across the United Kingdom: The Europain survey AID - 10.1136/archdischild-2014-306576.178 DP - 2014 Jun 01 TA - Archives of Disease in Childhood - Fetal and Neonatal Edition PG - A62--A62 VI - 99 IP - Suppl 1 4099 - http://fn.bmj.com/content/99/Suppl_1/A62.2.short 4100 - http://fn.bmj.com/content/99/Suppl_1/A62.2.full SO - Arch Dis Child Fetal Neonatal Ed2014 Jun 01; 99 AB - Background Pain and stress induced by mechanical ventilation, invasive procedures, or painful diseases supports the use of sedation/analgesia (S/A) in newborns admitted to Neonatal Units (NNUs). To date, these practices have not been studied on a large scale. Objective To determine current clinical practices regarding the use of S/A drugs in NNUs across the United Kingdom (UK). Design/Methods A European epidemiological observational study on clinical practices regarding bedside use of S/A collected data for all neonates in participating NNUs until the infant left the unit (discharge, death, transfer) or for up to 28 days. Data collection occurred via an online database for 1 month at each NNU. Neonates up to 44 weeks gestation were included. Results From February 2013 to May 2013, 66 UK NNUs collected data on 2691 eligible neonates. Of these, 713 received tracheal ventilation and 1978 had spontaneous breathing or non-invasive ventilation. The median (IQR) gestational age of ventilated neonates [32.1 (27.9–38.6)] was lower than for non-ventilated neonates [37.0 (34.1–39.7), p < 0.001]. Overall, more ventilated neonates [83.0% (n = 592)] received S/A drugs than non-ventilated neonates [7.4% (n = 147); p < 0.001]. The table shows S/A drugs used in ventilated neonates. View this table:Abstract PC.77 Table Conclusions Most ventilated but few non-ventilated neonates receive S/A therapy in UK NNUs. Wide variations in rates of S/A use and drugs used exist among centres.