TY - JOUR T1 - PFM.43 The antenatal detection of serious cardiac anomalies: A retrospective study from UHCW JF - Archives of Disease in Childhood - Fetal and Neonatal Edition JO - Arch Dis Child Fetal Neonatal Ed SP - A96 LP - A96 DO - 10.1136/archdischild-2014-306576.273 VL - 99 IS - Suppl 1 AU - L Spooner AU - L Lacey AU - S Mukherjee Y1 - 2014/06/01 UR - http://fn.bmj.com/content/99/Suppl_1/A96.1.abstract N2 - Introduction All pregnant women are offered an anomaly scan including assessment of fetal cardiac anatomy. Congenital cardiac disease is a complex structural malformation of the heart and/or great arteries requiring surgical/catheter intervention within the first 6 months.1 We reviewed the spectrum of defects diagnosed antenatally at our teaching hospital from 2011–2013 and identified if these were associated with a chromosomal defect, maternal disease, viral infection or a family history of cardiac disease. Methods Our fetal medicine database was used to identify 31 cases and the case notes to identify outcomes. View this table:Abstract PFM.43 Table View this table:Abstract PFM.43 Table Conclusions Three of our cases had a family history of congenital heart disease, two were associated with maternal diabetes and seven had a chromosomal abnormality. Twelve were diagnosed with HLHS making it the commonest antenatal diagnosis. Significant numbers of chromosomal defects emphasise the importance of thorough evaluation of any fetus identified with a cardiac defect. Reference Donald C. Fyler, MD. Report of the New England Regional Infant Cardiac Program. Pediatrics 1980;65(suppl):375–461 ER -