@article {WuA10, author = {P Wu and AD Cameron and JL Gibson and MA Ledingham and J Brennand}, title = {PF.20 Intrauterine Transfusion For Rhesus Isoimmunisation in Scotland}, volume = {98}, number = {Suppl 1}, pages = {A10--A10}, year = {2013}, doi = {10.1136/archdischild-2013-303966.032}, publisher = {BMJ Publishing Group}, abstract = {Scottish intrauterine transfusion (IUT) cases for severe Rhesus isoimmunisation over 2002{\textendash}2011 were reviewed. One hundred and forty-one pregnancies underwent 437 IUTs (mean 3.09, range 1{\textendash}8). One hundred and thirty-one fetuses had middle cerebral artery Doppler peak systolic velocity values documented. All were \>1.5 multiples of median prior to the first IUT, except for one that was inactive with a pericardial effusion. Twelve fetuses were hydropic. The haematocrit value prior to initial IUT was 20{\textendash}29\% in 38\% of cases, whilst 27\% had a haematocrit between 10{\textendash}19\%. Initial IUT was most commonly performed between 29{\textendash}32 weeks gestation (35\%) followed by 25{\textendash}28 (26\%) and 21{\textendash}24 (21\%) weeks gestation (range 17{\textendash}25 weeks). In the majority of cases, fetus was transfused via umbilical vein (80\%). Fourteen percent of transfusions were performed intrahepatically, 3\% intraperitoneally and 3\% were undocumented. Complications occurred in 58 (13\%) IUTs and include cord haematoma, difficult procedure, bradycardia or tachycardia necessitating unplanned delivery, and in utero death (5 fetuses). The procedure-related loss rate was 1\%. Birth outcomes were documented in 108 cases with a 94\% live birth rate (n = 102). One patient underwent termination of pregnancy for trisomy 21. Short term postnatal outcomes were available for 86 neonates: 33 neonates required phototherapy only, with 31 cases requiring top-up transfusions. Nine neonates had an exchange transfusion and 9 had immunoglobulin or erythropoietin. Four neonates did not require any treatment. We conclude that our live birth and procedure-related loss rates are consistent with other published series. Parents need to be aware of potential postnatal therapies.}, issn = {1359-2998}, URL = {https://fn.bmj.com/content/98/Suppl_1/A10.1}, eprint = {https://fn.bmj.com/content/98/Suppl_1/A10.1.full.pdf}, journal = {Archives of Disease in Childhood - Fetal and Neonatal Edition} }