TY - JOUR T1 - Bilateral retinoblastoma presenting at retinopathy of prematurity screening JF - Archives of Disease in Childhood - Fetal and Neonatal Edition JO - Arch Dis Child Fetal Neonatal Ed SP - F292 LP - F292 DO - 10.1136/adc.2009.178780 VL - 95 IS - 4 AU - J Self AU - K Bush AU - V R Baral AU - N Puvanachandra AU - V F Puddy AU - P Hodgkins Y1 - 2010/07/01 UR - http://fn.bmj.com/content/95/4/F292.abstract N2 - Diamniotic, dichorionic, male in vitro fertilisation (IVF) twins were born at 26+6 weeks. Retinopathy of prematurity screening revealed bilateral posterior pole retinoblastoma in twin A at 34 weeks' gestation. Aggressive chemoreduction therapy regressed the tumours significantly, which await definitive treatment (figure 1). Genetic analyses identified a heterozygous mutation in the RB1 gene in the affected twin that was absent … ER -