RT Journal Article SR Electronic T1 Pain in neonates during screening for retinopathy of prematurity using binocular indirect ophthalmoscopy and wide-fi eld digital retinal imaging: a randomised comparison JF Archives of Disease in Childhood - Fetal and Neonatal Edition JO Arch Dis Child Fetal Neonatal Ed FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP F146 OP F148 DO 10.1136/adc.2009.168971 VO 95 IS 2 A1 C A Dhaliwal A1 E Wright A1 N McIntosh A1 K Dhaliwal A1 B W Fleck YR 2010 UL http://fn.bmj.com/content/95/2/F146.abstract AB Objective To compare the pain experienced by premature infants undergoing wide-field digital retinal imaging (WFDRI) and binocular indirect ophthalmoscopy (BIO) for retinopathy of prematurity (ROP) screening. Methods Infants were recruited at Edinburgh Royal Infirmary Neonatal Unit, Edinburgh, UK. Eyes were examined by WFDRI and BIO with eyelid speculum by two experienced paediatric ophthalmologists in random order. A pain score (Premature Infant Pain Profile (PIPP)) for WFDRI and BIO was generated. Results A total of 76 infants were recruited. The (mean, SD) PIPP score for WFDRI was 15.0, 2.1 and for BIO was 15.2, 2.4 (paired t test p=0.47). The authors observed that infants started crying with corresponding physiological changes as soon as the eyelid speculum was inserted and crying stopped on speculum removal. Conclusion WFDRI and BIO with eyelid speculum are similarly painful for infants. The authors speculate that the eyelid speculum rather than the examination method may contribute most to the pain experienced.