TY - JOUR T1 - PDA and pulmonary hypertension: should the duct be ligated? JF - Archives of Disease in Childhood - Fetal and Neonatal Edition JO - Arch Dis Child Fetal Neonatal Ed SP - F75 LP - F75 DO - 10.1136/adc.2009.161786 VL - 95 IS - 1 AU - V A McCulloch AU - R M Tulloh Y1 - 2010/01/01 UR - http://fn.bmj.com/content/95/1/F75.1.abstract N2 - Patency of the arterial duct (PDA) in preterm infants is associated with myocardial dysfunction, risk of chronic lung disease (CLD), pulmonary haemorrhage,1 intraventricular haemorrhage (IVH), necrotising enterocolitis (NEC), renal insufficiency and retinopathy of prematurity (ROP),2 and non-steroidal therapy has significant risks.3 Surgical ligation is considered in those with contraindications or who fail to respond to medical treatment. Some do well and are rapidly extubated, but mortality after ligation is 20% with an incidence of CLD of 77%, IVH 33%, NEC 26% and ROP 28%.2 4One hundred and seventy-three consecutive … ER -