RT Journal Article SR Electronic T1 Contribution of inflammation to lung injury and development JF Archives of Disease in Childhood - Fetal and Neonatal Edition JO Arch Dis Child Fetal Neonatal Ed FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP F132 OP F135 DO 10.1136/adc.2004.068544 VO 91 IS 2 A1 S G Kallapur A1 A H Jobe YR 2006 UL http://fn.bmj.com/content/91/2/F132.abstract AB Inflammation interferes with lung development in model systems and is present chronically in the lungs of preterm infants who develop bronchopulmonary dysplasia (BPD). Antenatal inflammation is very commonly associated with preterm deliveries, but there is generally minimal information about the duration, intensity, or organisms associated with chorioamnionitis. In preterm lamb models, chorioamnionitis causes a lung injury similar to BPD and also causes clinical lung maturation. Continuous exposure of the developing lung before and after delivery to inflammation may be central to the development of BPD.