PT - JOURNAL ARTICLE AU - Y Nako AU - A Tachibana AU - T Fujiu AU - T Tomomasa AU - A Morikawa TI - Neonatal thrombocytosis resulting from the maternal use of non-narcotic antischizophrenic drugs during pregnancy AID - 10.1136/fn.84.3.F198 DP - 2001 May 01 TA - Archives of Disease in Childhood - Fetal and Neonatal Edition PG - F198--F200 VI - 84 IP - 3 4099 - http://fn.bmj.com/content/84/3/F198.short 4100 - http://fn.bmj.com/content/84/3/F198.full SO - Arch Dis Child Fetal Neonatal Ed2001 May 01; 84 AB - Neonatal thrombocytosis can result from maternal narcotic drug abuse. The case of a male infant is reported who was born to a woman with schizophrenia treated with non-narcotic psychotropic drugs during pregnancy; he developed severe prolonged thrombocytosis. The platelet count reached 1310 × 109/l on day 15. This thrombocytosis persisted for three months. The patient was treated with dipyridamole. A bone marrow aspirate showed normal myeloid and erythroid precursors with an increased number of megakaryocytes. Plasma concentrations of interleukin 6 and thrombopoietin were suppressed. No obvious complications from the thrombocytosis occurred, and the platelet count fell to within the upper limit of normal after 3 months of age. This case indicates that thrombocytosis may occur in infants born to mothers treated with non-narcotic psychopharmaceutical drugs during pregnancy. The thrombocytosis in this case may have been induced by factors other than interleukin 6 or thrombopoietin.