TY - JOUR T1 - Neonatal thrombocytosis resulting from the maternal use of non-narcotic antischizophrenic drugs during pregnancy JF - Archives of Disease in Childhood - Fetal and Neonatal Edition JO - Arch Dis Child Fetal Neonatal Ed SP - F198 LP - F200 DO - 10.1136/fn.84.3.F198 VL - 84 IS - 3 AU - Y Nako AU - A Tachibana AU - T Fujiu AU - T Tomomasa AU - A Morikawa Y1 - 2001/05/01 UR - http://fn.bmj.com/content/84/3/F198.abstract N2 - Neonatal thrombocytosis can result from maternal narcotic drug abuse. The case of a male infant is reported who was born to a woman with schizophrenia treated with non-narcotic psychotropic drugs during pregnancy; he developed severe prolonged thrombocytosis. The platelet count reached 1310 × 109/l on day 15. This thrombocytosis persisted for three months. The patient was treated with dipyridamole. A bone marrow aspirate showed normal myeloid and erythroid precursors with an increased number of megakaryocytes. Plasma concentrations of interleukin 6 and thrombopoietin were suppressed. No obvious complications from the thrombocytosis occurred, and the platelet count fell to within the upper limit of normal after 3 months of age. This case indicates that thrombocytosis may occur in infants born to mothers treated with non-narcotic psychopharmaceutical drugs during pregnancy. The thrombocytosis in this case may have been induced by factors other than interleukin 6 or thrombopoietin. ER -