PT - JOURNAL ARTICLE AU - Papoff, Paola AU - Christensen, Robert D AU - Harcum, Jenny AU - Li, Yan TI - In vitro effect of dexamethasone phosphate on hematopoietic progenitor cells in preterm infants AID - 10.1136/fn.78.1.F67 DP - 1998 Jan 01 TA - Archives of Disease in Childhood - Fetal and Neonatal Edition PG - F67--F69 VI - 78 IP - 1 4099 - http://fn.bmj.com/content/78/1/F67.short 4100 - http://fn.bmj.com/content/78/1/F67.full SO - Arch Dis Child Fetal Neonatal Ed1998 Jan 01; 78 AB - The in vitro effect of dexamethasone on the clonal growth of haematopoietic progenitors in preterm infants was investigated. Concentrations of 106M to 109M were associated with a dose dependent inhibition of colony formation, with the most clinically important effects seen on the earliest erythroid and granulocyte-macrophage colonies. Because of the potential clinical implications of these observations, studies are needed to determine the effects of dexamethasone on haematopoiesis in preterm infants.