TY - JOUR T1 - Neonatal symptomatic thromboembolism in Germany: two year survey JF - Archives of Disease in Childhood - Fetal and Neonatal Edition JO - Arch Dis Child Fetal Neonatal Ed SP - F163 LP - F167 DO - 10.1136/fn.76.3.F163 VL - 76 IS - 3 AU - Ulrike Nowak-Göttl AU - Rüdiger von Kries AU - Ullrich Göbel Y1 - 1997/05/01 UR - http://fn.bmj.com/content/76/3/F163.abstract N2 - AIMS To determine the incidence of neonatal thromboembolism in Germany. METHODS Diagnostic imaging techniques, therapeutic modalities, and short term outcome were evaluated in a prospective nationwide two year case registry study. RESULTS The reported incidence of symptomatic neonatal thromboembolism, diagnosed in most cases with Doppler ultrasonography, was 5.1 per 100 000 births, with a total of 79 cases registered: renal venous thrombosis (n=35); venous thrombosis (n=25); and arterial vascular occlusion (n=19). Fifty seven of 79 thromboses were associated with additional risk factors (central line n=25, asphyxia n=13, septicaemia n=11, dehydration n=6, maternal diabetes n=2, cardiac disease n=1). Inherited thrombophilia was also diagnosed in seven out of 35 cases investigated. Twenty three children received supportive treatment: 42 received heparin and in 13 neonates thrombolytic agents were administered. Most neonates (91%) survived; seven died. CONCLUSION Controlled multicentre studies are needed to obtain more information on treatment efficacy. ER -