@article {Nowak-G{\"o}ttlF163, author = {Ulrike Nowak-G{\"o}ttl and R{\"u}diger von Kries and Ullrich G{\"o}bel}, title = {Neonatal symptomatic thromboembolism in Germany: two year survey}, volume = {76}, number = {3}, pages = {F163--F167}, year = {1997}, doi = {10.1136/fn.76.3.F163}, publisher = {BMJ Publishing Group}, abstract = {AIMS To determine the incidence of neonatal thromboembolism in Germany. METHODS Diagnostic imaging techniques, therapeutic modalities, and short term outcome were evaluated in a prospective nationwide two year case registry study. RESULTS The reported incidence of symptomatic neonatal thromboembolism, diagnosed in most cases with Doppler ultrasonography, was 5.1 per 100 000 births, with a total of 79 cases registered: renal venous thrombosis (n=35); venous thrombosis (n=25); and arterial vascular occlusion (n=19). Fifty seven of 79 thromboses were associated with additional risk factors (central line n=25, asphyxia n=13, septicaemia n=11, dehydration n=6, maternal diabetes n=2, cardiac disease n=1). Inherited thrombophilia was also diagnosed in seven out of 35 cases investigated. Twenty three children received supportive treatment: 42 received heparin and in 13 neonates thrombolytic agents were administered. Most neonates (91\%) survived; seven died. CONCLUSION Controlled multicentre studies are needed to obtain more information on treatment efficacy.}, issn = {1359-2998}, URL = {https://fn.bmj.com/content/76/3/F163}, eprint = {https://fn.bmj.com/content/76/3/F163.full.pdf}, journal = {Archives of Disease in Childhood - Fetal and Neonatal Edition} }