PT  - JOURNAL ARTICLE
AU  - H Soltani-K
AU  - C Bruce
AU  - R B Fraser
TI  - Observational study of maternal anthropometry and fetal insulin
AID  - 10.1136/fn.81.2.F122
DP  - 1999 Sep 01
TA  - Archives of Disease in Childhood - Fetal and Neonatal Edition
PG  - F122--F124
VI  - 81
IP  - 2
4099  - http://fn.bmj.com/content/81/2/F122.short
4100  - http://fn.bmj.com/content/81/2/F122.full
SO  - Arch Dis Child Fetal Neonatal Ed1999 Sep 01; 81
AB  - AIMS To examine the relation between maternal body fat and fetal metabolism. METHODS In this observational study, cord blood samples were collected from 60 infants of healthy women for the measurement of insulin and C peptide concentrations. Maternal weight, height, body mass index (BMI) and body composition (skinfold thickness measurements and bioelectrical impedance) were assessed at 13–15 weeks of gestation. Twenty five of the volunteers agreed to have a 75 g oral glucose tolerance test at 28–31 weeks of gestation. RESULTS Positive correlations were observed with both cord insulin or C peptide concentrations and maternal early pregnancy BMI (r=0.44, p=0.002 and r=0.33, p=0.008, respectively). There was no significant correlation between cord insulin or C peptide concentrations and birthweight or birth weight centiles. CONCLUSION Maternal BMI could be a predictor of fetal cord insulin concentration.