TY - JOUR T1 - Neonatal varicella: varicella zoster immunoglobulin (VZIG) does not prevent disease JF - Archives of Disease in Childhood - Fetal and Neonatal Edition JO - Arch Dis Child Fetal Neonatal Ed SP - F69 LP - F70 DO - 10.1136/fn.81.1.F69 VL - 81 IS - 1 AU - Lucy Reynolds AU - Siske Struik AU - Simon Nadel Y1 - 1999/07/01 UR - http://fn.bmj.com/content/81/1/F69.abstract N2 - Two infants with severe varicella are reported. They received varicella zoster immunoglobulin (VZIG) without concurrent information to parents or carers regarding further care. In both these cases there was a three day delay between the onset of symptoms and initiation of aciclovir. This delay was due to lack of awareness of the high risk of varicella in these infants.  Infants born to mothers with onset of chickenpox 4 days before to 2 days after delivery are at risk of fatal varicella, despite the use of VZIG prophylaxis. ER -