RT Journal Article SR Electronic T1 Neonatal abstinence syndrome after maternal methadone treatment. JF Archives of Disease in Childhood - Fetal and Neonatal Edition JO Arch Dis Child Fetal Neonatal Ed FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP F203 OP F205 DO 10.1136/fn.71.3.F203 VO 71 IS 3 A1 N J Shaw A1 L McIvor YR 1994 UL http://fn.bmj.com/content/71/3/F203.abstract AB Thirty two infants born to mothers taking methadone and 32 matched controls were studied to determine the incidence, timing, and frequency of persistence of withdrawal signs in infants born to maternal methadone users. Twelve (37%) infants received treatment for symptoms of withdrawal. The median length of time from birth to initiation of treatment was 23 hours (range 15-64 hours), the median length of treatment was six days (range 1-22 days). In the first six weeks after birth there was no significant difference in minor withdrawal symptoms and signs, general practitioner or accident and emergency visits between the group who did not receive treatment for withdrawal and the control group. If immediate treatment for withdrawal is not required major symptoms do not subsequently occur with great frequency. Late withdrawal signs were not seen in this study.