RT Journal Article SR Electronic T1 Haemodynamic changes during high frequency oscillation for respiratory distress syndrome. JF Archives of Disease in Childhood - Fetal and Neonatal Edition JO Arch Dis Child Fetal Neonatal Ed FD BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health SP F172 OP F176 DO 10.1136/fn.74.3.F172 VO 74 IS 3 A1 Laubscher, B. A1 van Melle, G. A1 Fawer, C. L. A1 Sekarski, N. A1 Calame, A. YR 1996 UL http://fn.bmj.com/content/74/3/F172.abstract AB In a crossover trial left ventricular output (LVO), cerebral blood flow velocity (CBFV), and resistance index (RI) of the anterior cerebral artery were compared using Doppler ultrasonography, in eight preterm infants with respiratory distress syndrome (RDS) during conventional mechanical ventilation and high frequency oscillation. LVO was 14% to 18% lower with high frequency oscillation. There were no significant changes in CBFV. On the first day of life there was a trend towards lower RI on high frequency oscillation; the fall in LVO on high frequency oscillation was not related to lung hyperinflation. Changes in ventilation type (from conventional mechanical ventilation to high frequency oscillation, or vice versa) can induce significant LVO changes in preterm infants with RDS.