PT - JOURNAL ARTICLE AU - Walter, J. H. AU - Wraith, J. E. AU - Cleary, M. A. TI - Absence of acidosis in the initial presentation of propionic acidaemia. AID - 10.1136/fn.72.3.F197 DP - 1995 May 01 TA - Archives of Disease in Childhood - Fetal and Neonatal Edition PG - F197--F199 VI - 72 IP - 3 4099 - http://fn.bmj.com/content/72/3/F197.short 4100 - http://fn.bmj.com/content/72/3/F197.full SO - Arch Dis Child Fetal Neonatal Ed1995 May 01; 72 AB - The clinical presentation and results of the initial biochemical and haematological investigations in 11 newborn term infants with propionic acidaemia are described. All patients had neurological symptoms. Only four had clinically important acidosis, but all had a raised blood ammonia. A diagnosis of propionic acidaemia should be considered in all newborn infants with unexplained neurological deterioration even in the absence of a metabolic acidosis.