71 e-Letters

published between 2011 and 2014

  • Do not forget cystic fibrosis
    Samuele Naviglio

    I read with interest the article by Best et al. regarding the epidemiology of small intestinal atresia. In the evaluation on the associated conditions nevertheless the Authors do not include nor mention the association of intestinal atresia with cystic fibrosis. In fact this is an association which should never be forgotten while caring for an infant with small intestinal atresia. Up to 13% of children with jejunoileal...

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  • "SHC" versus "WBC" in therapeutic hypothermia for HIE
    Biju M John

    Dear Editor, We read with interest the article by Sarkar et al(1) on distribution and severity of hypoxic-ischaemic lesions on brain MRI following therapeutic cooling .It is perhaps one of the very few studies which has attempted to look at the possible differences between the two forms of cooling for hypoxic ischemic encephalopathy(HIE).Brain MRI is increasingly being utilized as a good biomarker of long term neurologi...

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  • Re:Response to: Drugs used for comfort care after withdrawal of intensive treatment in tertiary neonatal units in the UK1.
    Rajiv Chaudhary

    Dear sir I am grateful for Dr. Power's comments and the opportunity to respond to them. We do know that withdrawal of intensive treatment can pose many challenges. Once decision is agreed to withdraw intensive treatment a significant time elapses before ventilatory support is withdrawn. This duration is very much dependent on individual cases and is guided by clinical, social, religious and familial factors. Respirator...

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  • Minimally, moderately, or ... equally invasive surfactant therapy?
    Paolo Biban

    Dear Editor, I read with interest the article by Dargaville et al (1), about the feasibility and potential effectiveness of MIST, i.e. minimally-invasive surfactant therapy, in preterm infants with respiratory distress syndrome. Similarly to other recent techniques (2,3), the ultimate goal of MIST is that of delivering surfactant while avoiding both "standard" tracheal intubation and mechanical ventilation. The authors ha...

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  • Subcutaneous air
    Kenneth L Harkavy

    The authors present an infant whose free air spread from the thorax to the neck and scalp. Many years ago we reported a term infant with subcutaneous air. At a community hospital the infant developed a pneumothorax and possible pneumomediastinum. Over the course of four hours, he progressed to bilateral tension pneumothoraces. The transport team performed bilateral thoracenteses at 5 hours of age. Chest drains were plac...

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  • The new model of continuous glucose monitoring sensor "ENLITE" in preterm infants.
    Enrico Zecca

    Dear Editor, We read with interest the paper by K Beardsall et al about the validation of the continuous glucose monitoring sensor (CGMS) in preterm infants (1). In this study the author confirms in a large population the good results of her previous pilot study (2). Apparently, the recent study utilized the first model of Medtronic CGMS, whose sensor was linked to the monitor and did not have real time read outs. Howe...

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  • Response to: Fetal Surgery for Neural Tube Defects
    Paul A Leach

    Letter to the Editor

    Response to: Niforatos N, du Pessis A. Arch Dis Child Fetal Neonatal Ed. Fetal surgery for neural tube defects. 2012 May 18. [Epub ahead of print]

    Dear Editor,

    I read with interest the review article by Niforatos and du Plessis1 regarding antenatal closure of myelomeningoceles (MMC), concentrating on the recent publication of the MOMS trial2. The authors make the comment...

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  • High dose erythropoietin in preterm infants for neuroprotection does not increase the risk for haemangioma
    Hans Ulrich Bucher

    Based on a retrospective study, Doege et al. reported an increased incidence of haemangioma after treatment with erythropoietin. To verify these results, we did an interim analysis in an on-going prospective randomized placebo-controlled multicentre trial comparing high dose recombinant human erythropoietin (rhEpo) 3,000 U/kg body weight with NaCl 0.9% intravenously at 3, 12-18 and 36-42 hours after birth (NCT00413946)....

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  • Significance of Intermediate onset sepsis in neonate?
    Praveen Bagalkot

    Respected Editor,

    It was interesting to read the article on multi drug resistance gram negative sepsis in neonates from India. I have certain concern about the research article which are as follows:

    1) Standard medical literature on neonatal sepsis mentions Early onset sepsis (EOS) and late onset sepsis (LOS).1,2, The authors have not mentioned the reason for including intermediate onset sepsis (IOS) in...

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  • Methods of weaning preterm babies
    Srinivas Murki


    We have read with interest the article " Methods of weaning preterm babies <30 weeks gestation off CPAP: a multicentre randomised controlled trial", which has shown that weaning directly from CPAP to room air or crib oxygen was successful rather than to nasal prong and ON/ OFF method of CPAP.

    Surprisingly, the authors were silent on few issues like 1. The CPAP pressure at weaning (whether it wa...

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