eLetters

228 e-Letters

published between 2002 and 2005

  • Re: Recording of central venous line tips post insertion
    David W Cartwright

    Dear Editor,

    Dr Asumang in her eletter, in response to my recently published audit of peripherally inserted central venous catheters (PICCs) in neonates, questions the details of the location of line tips, and the determination and recording of tip positions.

    Tip positions were – right atrium (1282), SVC (239), subclavian vein (203), limb vein (100), IVC (98), jugular vein (71), innominate vein (61), ne...

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  • Neonatal disease severity score systems: more points for debate?
    Giuseppe Latini

    Dear Editor,

    We read with great interest the review by Dorling et al [1]. on neonatal illness severity score systems (NISS), in which the authors have thoroughly examined the strengths and weaknesses of the existing methods. We would like to add a few points to the ongoing debate [2] on the usefulness and limitations of the NISS.

    Assessment of illness severity in the newborn is of paramount impo...

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  • A safe alternative to alcohol-based local antiseptics in very immature newborn infants
    Christoph Bührer

    Dear Editor,

    Reynolds et al report on a very immature newborn infant who suffered severe skin damage after periumbilical administration of an alcohol-based antiseptic [1]. The burned skin may serve as a microbial entry port and give rise to lasting scars [2]. After topical skin application, ethanol or propanol cause substantial decreases of functional capillary density and red blood cell velocity, which is...

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  • Knotted cords in monoamniotic twins are not benign
    Janet M Rennie

    Dear Editor,

    Omari and Cameron are not quite right when they extrapolate from the literature on knotted cords in singleton pregnancies to the particular situation of monochorionic monoamniotic twins. It is true to point out that a single true knot in the cord is rarely of significance when there is one baby, although on occasion even these can tighten and cause hypovolaemic shock and/or hypoxic ischaemia.

    ...
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  • Bronchiolitis hospital admissions of infants less than 32 weeks of gestation
    Heracles D Dellagrammaticas

    Dear Editor,

    We read with interest the study by Heikkinen et al [1] and the letter by Bala, Ryan and Murphy [2] on bronchiolitis hospital admissions and of Palivizumab prophylaxis. We would like to add our experience on the issue.

    Our retrospective study covered the period from 01.01.1995 to 31.12.2000 i.e. a 6-year period before Palivizumab prophylaxis became available in Greece. We looked into hosp...

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  • Lipopolysaccharide binding protein in preterm infants
    Sudhin Thayyil

    Dear Editor,

    Congratulations to Behrendt and team for introducing yet another infection marker in premature babies [1]. However, there are several flaws in the study design which could render the study conclusions not clinically useful.

    The authors repeatedly mention the aim of their study was to look at lipopolysaccharide binding protein (LBP) levels in premature babies. Results quoted however includ...

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  • Loss of antioxidants in breastmilk: what is the clinical relevance?
    Alicia R Dermer, MD

    Dear Editor,

    The study on storage of breastmilk and its effect on antioxidant levels [1] was well designed and provided some interesting information. However, the conclusions that the authors drew are based on conjecture about the clinical relevance of the findings. There is a potential risk to infant health if mothers follow their recommendations and abandon the pumping and storage of their milk.

    The authors...

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  • Yes, human milk does reduce infection rates in VLBW infants
    Lydia Furman

    Dear Editor,

    Drs. De Silva, Jones and Spencer have provided a timely review of issues relating to studies of breastmilk feeding for VLBW infants and rates of infection [1]. We would appreciate the opportunity to clarify some points they have raised regarding our study [2]. We believe our results clearly support our conclusion: that intake of greater than 50 ml/kg/day of maternal milk through week four of life...

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  • Reply to : Septic infants: Pandora box reopens
    Dror Mandel

    Dear Editor

    We appreciate the interest of Dr Gupta and his thoughtful comments.[1]

    1. Primary disease of the neonates included in the study: Our original submission to the journal included a complete table describing in many more details the patient population. At the request of the reviewers/editors to shorten the paper, we removed the table which is now attached at the end of this letter.

    2. Antibiot...

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  • Inadvertent overdosing of neonates due to dead space of syringe hub and needle
    Vikas Bhambhani

    Dear Editor,

    Chappell and Newman [1] have asked for urgent initiatives needed to ensure the manufacture of neonatal targeted products to reduce the risks associated with intravenous drug administration. We endorse their view and report a little recognized problem with use of adult formulations in neonatal nurseries

    This investigation was conducted after we noticed symptoms of Digoxin overdose (brady-arrhythmia)...

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