110 e-Letters

published between 2008 and 2011

  • Lingual mass in a neonate : do not forget the thyroid
    Diane Rottembourg

    In their article Joolay and Stewart report the occurrence of a rare case of congenital lingual teratoma (1). The 19 mm mass was even discovered prenatally on ultrasound. In the differential diagnosis of an oral mass discovered in the fetus or in the neonate, the authors omitted to mention the possibility of an ectopic lingual thyroid. The occurrence of an ectopic thyroid is due to abnormal migration of the gland during...

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  • A case of prenatal cerebellar haemorrhage in a late preterm infant
    Chiara Protano
    Dear Editor, in the article by McCarthy it emerged that cerebellar haemorrhage (CBH) is a rare condition typical of extreme prematurity, with male preponderance, and which always results in a very severe prognosis. We would like to present a case of CBH with different characteristics, as it appeared prenatally in a late preterm infant who finally survived. The baby was born at 35 weeks of GA by caesarean section for a worsening v...
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  • Procalcitonin for early diagnosis of neonatal nosocomial sepsis
    Claudio Chiesa

    We have read with interest the paper by Cinzia Auriti et al (1) on the accuracy of procalcitonin (PCT) as a diagnostic marker of nosocomial sepsis in neonates. However, we believe that there are a number of points that should be addressed. First, it is not clear which "fast" PCT assay was actually used. The authors state that it was a quantitative immunoluminometric method (Lumitest PCT-Q, BRAHMS), but according to the...

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  • Error in the article
    Keith J Barrington
    The analysis by Yates and Newell points out the need for new trials to determine if there is a safe and effective way to give postnatal steroids for preterm infants. A conclusion that I can only agree with. However their article is limited by one major error, and by the failure to describe one of the serious limitations of the available evidence. The Major error is contained in the section "CLD severity and CP risk". The authors s...
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  • Sudden Unexplained Neonatal Deaths
    Giulia Ottaviani

    The author has read with great interest the report of Leow and Ward Platt (1), who accurately studied the incidence of sudden, unexpected and unexplained early neonatal deaths in the North of England giving an overall rate of 0.35/10,000 live births. While several works have stressed the importance of post-mortem examination in every case of suspected sudden infant death syndrome (SIDS), little, if any, attention has bee...

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  • global burden of neonatal hyperbilirubinemia rather rh heolytic disease
    sudarshan kumari

    The article "Global Burden of Rh hemolytic disease" is an excellent article, highlighting the problem, statistics of the problem and preventive aspect. No doubt rh hemolytic disease is preventable as examplified in developing countires by antenatal rh group testing of mothers,use of anti-d and iv immunoglobulin in affceted neonates, along with effective phototherapy . In developing countries and in India, data from inst...

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  • Ibuprofen and Chronic lung disease association: Is this clinically significant?
    Stanley Tso

    Dear Sir,

    We read the article by Jones et al with great interest describing Ibuprofen may increase the risk of chronic lung disease (CLD) compared to Indomethacin. We are unsure whether the data presented is fully supportive of the conclusion that Ibuprofen poses a greater risk of CLD compared to Indomethacin and whether this is clinically significant.

    In Figure 4 the pooled risk ratio (RR) was 1.28 (95...

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  • Although a model is low-cost its transfer from developed to developing countries is not necessarily a priority
    Maurizio Bonati

    Dear Editor,

    During the past five years, therapeutic hypothermia (TH) was shown to be effective and safe in improving neurodevelopmental outcome after hypoxic ischaemic encephalopathy (HIE) in newborns.(1) The use of this therapy has been rapidly incorporated into clinical practice in many countries, even though many doubts related to clinical management and monitoring remain unanswered.(2) The lack of a national appro...

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  • Instability of cerebral blood flow in asphyxiated infants with developmental delay
    Kazunari Kaneko

    Dear Sir,

    We read this paper with interest and would like to comment. The authors have concluded that there is little evidence that early postnatal hypotension indicators are associated with developmental delay at 24 months corrected in their large cohort of extremely low gestational age newborns.

    We agree with their conclusion as our recent study in 11 asphyxiated term infants demonstrated the simila...

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  • Response: Chorioamnionitis, lung function and bronchopulmonary dysplasia in prematurely born infants
    Neil Everest

    Dear Sir,

    The article by Prendergast et al describes an important outcome following a very common antenatal complication. However, there is no description of the proportion of infants surviving in the two groups which may overshadow any lack of difference in BPD development between the two groups. In the statistical methods no assessment appears to have been made in the regression model between duration of membrane...

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