183 e-Letters

published between 2004 and 2007

  • Conservative treatment of symptomatic patent ductus arteriosus beyond the first week of life
    Jasper V Been

    Bose and Laughon have clearly reviewed the lack of evidence for current treatments of patent ductus arteriosus (PDA) in preterm infants.[1] As highlighted, the general tendency to treat a clinically relevant PDA for fear of adverse clinical outcome with either indomethacin or surgery when indomethacin fails has caused a lack of information on the natural history of symptomatic PDA. Spontaneous PDA closure has been report...

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  • Prevalence and pathogenesis of congenital anomalies in cerebral palsy - letter to editor
    Maria A Loane
    Peter Pharoah conducted a study comparing the livebirth prevalence of congenital anomalies in children with CP living in Merseyside UK to the prevalence of congenital anomalies in 8 UK EUROCAT population-based congenital anomaly registers 1. EUROCAT is a European network of population-based registries for the epidemiologic surveillance of congenital anomalies. Currently, the network consists of 39 active registries in 20 count...
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  • Prophylaxis to reduce fungal infection in neonates
    Renato S Procianoy

    The study by McCrossan et al showed that fluconazole prophylaxis in a selected group of preterm infants with birth weight less than 1,500 grams decreases invasive fungal infection [1]. We agree that a carefully delineated risk-factor approach to the prevention of Candida infection in neonates may be a useful alternative to continuous fluconazole prophylaxis and may decrease the risk of the emergence of fluconazole-resistan...

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  • Group B Streptococcus and preventive strategies in Europe
    Alberto Berardi

    Berardi A (1), Lugli L (1), Rossi C (2), Morini MS (3), Vagnarelli F (4), Ferrari F (1)

    1 Unità Operativa di Neonatologia, Dipartimento Materno-Infantile, Azienda Ospedaliero-Universitaria Policlinico di Modena

    2 Unità Operativa di Pediatria, Dipartimento Materno-Infantile, Azienda Ospedaliero-Universitaria Policlinico di Modena

    3 Unità Operativa di Pediatria, Ospedale Pierantoni, Forlì

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  • This may be explained by DHEA Levels
    James M. Howard

    It is my hypothesis that all tissues rely on DHEA for optimal function. Low DHEA has been found in preterm infants (Acta Paediatr. 2007 Nov;96(11):1600-5). I suggest this may be due to reduced availability of maternal DHEA as the infant does not start producing its own DHEA until birth.

    It is also my hypothesis that SIDS results from excessively low DHEA during sleep which results in lack of support of brainst...

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  • Improving point of care delivery
    Shan S Tang

    We read with interest the use of blood gas analysis for estimation of haemoglobin concentration compared with laboratory measurement performed by Lucy et al at the Royal Hallamshire Hospital (1).

    In the neonatal unit in Homerton University Hospital, we record the haematocrit in the observation charts. The measurements of haematocrit used are from blood gas results obtained from the Radiometer ABL 700 series blo...

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  • Does “Carta di Firenze” correspond to the opinion of Italian neonatologists?
    Daniele Trevisanuto

    We read with interest Pignotti et al’s paper on perinatal care at an extremely low gestational age (22-25 weeks).1 This consensus document represents “an Italian approach” and it was evaluated by several scientific societies. It is a very interesting document, but, unfortunately, it does not fit with the opinion of the Italian neonatologists. For example, the document suggests “palliative care, unless the infant shows s...

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  • This could be due to low DHEA
    James M. Howard

    It is my hypothesis that all tissues rely on DHEA for optimal function. Low DHEA has been found in preterm infants (Acta Paediatr. 2007 Nov;96(11):1600-5). Protective effects of DHEA against many infectious agents has also been determined.

    I suggest the findings of Bartels, et al., may be explained by low DHEA. That is, a common cause of low DHEA may be involved in growth retardation in preterm infants and th...

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  • Infant Directed Speech and Frontal Lobes
    Stefano Bembich

    Saito et al.1 showed, by means of a two channel NIRS, a differential response of the neonatal brain to maternal Infant Directed Speech (IDS), in comparison to Adult Directed Speech (ADS). Their study is very interesting. They hypothesize that a newborn is able to distinguish between different emotional communications in the first days of life. These results reignite the discussion on early predisposition for newborns’...

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  • Point of care estimation in neonates: not just for haemoglobin
    Owen J Arthurs

    Dear Editor,

    We read with interest the article by Hinds et al [1] comparing laboratory and blood gas analyser haemoglobin on their NICU. They found a good correlation between laboratory measures and the ABL725 Radiometer blood gas analyser in 127 babies on their unit. However, we feel that the focus of their article was somewhat limited, as they assessed haemoglobin and haematocrit alone. Blood gas analysers ha...

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