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Ophthalmic Pseudomonas infection in infancy

Abstract

Four infants developed invasive Pseudomonas aeruginosa ophthalmic infections between 5 and 90 days of age. Three died from septicaemia, and the fourth required enucleation of one eye. Absent red reflexes or other eye signs in a septicaemic infant merit urgent ophthalmological assessment for endophthalmitis, in particular, Pseudomonas.

Key messages

Key messages

  • Loss of red reflex, a change in the appearance of the iris, or purulent eye discharge can be clues to a life threatening ocular and systemic infection

  • Bilateral endophthalmitis can complicate neonatal pseudomonal septicaemia, and is a grave prognostic sign for survival

  • Treatment of neonatal endophthalmitis should include intravitreal and intravenous antibiotics

  • Pseudomonas aeruginosa
  • eye
  • endophthalmitis
  • bacteria
  • infection

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